word
synaptic pruning
sih-NAP-tik PROO-ning
sɪˈnæptɪk ˈpruːnɪŋListen
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Syllable breakdown
synapticpruning
Dictionary meaning
the developmental process by which excess synaptic connections formed during early brain development are selectively eliminated to increase the efficiency and specificity of neural circuits; occurs extensively during infancy, childhood, and adolescence and is guided by patterns of neural activity on the principle that connections that fire together wire together and unused connections are removed; abnormalities in synaptic pruning have been implicated in schizophrenia, autism spectrum disorder, and other neurodevelopmental conditions
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