regulatory T cell
REG-yoo-lah-tor-ee TEE SEL
ˈrɛɡjʊlətɔːri tiː sɛlListen
Hear it in a clear American voice. Slow it down to catch each syllable.
Syllable breakdown
Dictionary meaning
a specialised subtype of CD4+ T lymphocyte characterised by expression of the transcription factor FoxP3 that suppresses excessive immune responses to prevent autoimmunity, chronic inflammation, and immunopathology; regulatory T cells, sometimes called Tregs, maintain immune tolerance to self-antigens and harmless environmental antigens by secreting immunosuppressive cytokines such as IL-10 and TGF-beta and by directly inhibiting the activation and proliferation of effector T cells and antigen-presenting cells; dysfunction or deficiency of regulatory T cells contributes to autoimmune diseases including type 1 diabetes, rheumatoid arthritis, and multiple sclerosis
Learn one new pronunciation a day
Get a word, name or idiom like “regulatory T cell” in your inbox — daily or weekly, free. Unsubscribe any time.