evidence-based medicine
EV-ih-dents BAYST MED-ih-sin
ˈɛvɪdəns beɪst ˈmɛdɪsɪnListen
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Dictionary meaning
an approach to clinical practice that integrates the best available research evidence with individual clinical expertise and patient values in making decisions about the care of individual patients; coined by Gordon Guyatt and colleagues at McMaster University in 1992 and further developed by David Sackett, EBM challenged the reliance on expert opinion, pathophysiological reasoning, and clinical tradition as primary bases for treatment decisions, insisting instead on rigorous appraisal of evidence from clinical trials, systematic reviews, and epidemiological studies; evidence-based medicine established a hierarchy of evidence in which randomised controlled trials and meta-analyses are considered most reliable, and has profoundly shaped medical education, clinical guidelines, and health technology assessment
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