word
coagulation cascade
koh-AG-yoo-LAY-shun kah-KAYD
koʊˌæɡjʊˈleɪʃən kæˈkeɪdListen
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Syllable breakdown
coagulationcascade
Dictionary meaning
series of enzymatic reactions in which clotting factors activate each other in sequence, ultimately producing fibrin that meshes with platelets to form a blood clot; divided into intrinsic, extrinsic, and common pathways; disruptions in any step cause bleeding disorders such as hemophilia; anticoagulant drugs work by interrupting specific points in the cascade
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